In een interview met MCV heeft screenwriter Neil Druckmann gezegd dat de film in sommige scenes iets anders zal zijn dan in de game. Volgens Neil is het niet mogelijk om een verhaal – wat in de game zo’n 15 uur duurt – te vertalen naar een film die zo’n 2 uur zal duren.

“In two hours you can’t tell the same kind of story that you can in a game like The Last of Us, which is 15 hours,”

“I’m in the middle of it now, and it’s been super difficult because there’s so much that happens in The Last of Us – even just in the cinematics – that can’t fit in a film, let alone all the gameplay in-between and dialogue.”

“It’s been really difficult to cut certain things out, but what I’m starting to get this is really focused narrative that’s about these two characters,” he said. “Some parts will be similar to the game and some parts will be quite different, but it’s kind of interesting in helping me understand this other medium and its strengths compared to video games.”

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